Can cause side effects such as hot flashes, fatigue, decreased libido, and nausea, with some patients experiencing breast tenderness or gastrointestinal issues. More serious side effects may include liver toxicity, osteoporosis, cardiovascular problems, and mood changes, so regular monitoring is essential. Additionally, patients may experience weight gain, skin rashes, and anemia, and it's important to report any unusual symptoms to a healthcare provider for early intervention.

Bicalutamide (Casodex) carries several important warnings. It can cause severe liver damage, so liver function should be closely monitored during treatment, especially for those with pre-existing liver conditions. It may also increase the risk of heart problems, including heart failure and arrhythmias, and long-term use can lead to osteoporosis and an increased risk of fractures. Additionally, Bicalutamide may cause significant mood changes, including depression, and should be used with caution in patients with a history of mental health conditions. It's essential to seek medical advice immediately if any symptoms of liver problems (such as jaundice), heart issues, or mood changes occur.

An overdose of bicalutamide (Casodex) can lead to serious health complications, although it is generally considered to have a low risk of acute toxicity. Symptoms of an overdose may include severe dizziness, confusion, nausea, vomiting, and fatigue. In the case of a suspected overdose, it is important to seek immediate medical attention. Treatment typically involves supportive care to manage symptoms, as there is no specific antidote for bicalutamide overdose. Regular monitoring and prompt intervention are crucial to prevent serious complications. If an overdose is suspected, contacting poison control or going to the emergency room is recommended.