Is primarily used to treat intermittent claudication, a condition associated with peripheral artery disease (PAD), which causes painful cramping in the legs due to inadequate blood flow. By improving circulation, cilostazol helps increase walking distance and reduce pain during physical activity, thereby improving mobility and quality of life for people with PAD. In addition to its effects on circulation, cilostazol also has antiplatelet properties, which help reduce the risk of blood clots forming in the arteries.
Can cause several side effects, ranging from mild to more serious. Common side effects include headache, diarrhea, dizziness, palpitations (rapid heart rate), and fluid retention (swelling in the legs or ankles). While these side effects are generally mild, more serious effects can occur, such as tachycardia (abnormally fast heart rate), chest pain, shortness of breath, or severe dizziness. Due to its antiplatelet effects, cilostazol may also increase the risk of bleeding or bruising. People with heart failure should avoid using cilostazol as it can worsen their condition. If any severe symptoms, such as chest pain or difficulty breathing, occur, immediate medical attention should be sought.
Carries important warnings, especially for individuals with heart conditions. It should be avoided in people with heart failure (both congestive and non-congestive) because it may worsen the condition by increasing the workload on the heart and potentially leading to fluid retention. Cilostazol can also cause tachycardia (rapid heart rate) and palpitations, which may be problematic for individuals with pre-existing heart problems. Additionally, due to its antiplatelet effects, it can increase the risk of bleeding or bruising, and caution is advised in patients taking anticoagulants or antiplatelet medications. It should also be used with caution in individuals with liver or kidney problems, as these conditions can affect how the medication is metabolized. Regular monitoring of symptoms and close medical supervision are important while taking cilostazol.
An overdose of cilostazol (Pletal) may lead to exaggerated side effects, particularly tachycardia (rapid heart rate), palpitations, low blood pressure, and dizziness. Symptoms of overdose may also include severe headache, diarrhea, and increased bleeding or bruising due to the medication's antiplatelet effects. In cases of overdose, immediate medical attention is necessary. Treatment typically involves supportive care, which may include managing symptoms like low blood pressure or irregular heart rate. If severe bleeding or other complications arise, specific interventions may be required to address the overdose.