Hydralazine is primarily used to treat high blood pressure (hypertension) and heart failure. It works as a vasodilator, relaxing the blood vessels to improve blood flow, which helps to lower blood pressure and reduce the workload on the heart. Hydralazine is often prescribed when other blood pressure medications are ineffective or when patients cannot tolerate other treatments. In addition to its use for hypertension, hydralazine is also used to manage heart failure, particularly in combination with other medications. It can be used in acute settings for hypertensive crises to quickly lower dangerously high blood pressure and prevent complications like stroke or organ
Common side effects include headache, dizziness, nausea, flushing, and palpitations (rapid heartbeat). More serious side effects may include heart palpitations, swelling, chest pain, and, in rare cases, lupus-like symptoms such as joint pain and rashes.
Hydralazine should be used with caution in individuals with heart disease, kidney disease, or lupus, as it may exacerbate these conditions. It should not be used during pregnancy unless absolutely necessary, as it may have potential risks to the fetus. People who take hydralazine should be monitored regularly for side effects, particularly if they have a history of low blood pressure or heart conditions.