May cause a variety of side effects, ranging from mild to severe. Common side effects include muscle pain, weakness, headache, digestive issues like nausea, diarrhea, and indigestion, as well as fatigue and sleep disturbances like insomnia. Less common but serious side effects can include liver damage (indicated by symptoms like yellowing skin or eyes, dark urine, and stomach pain), muscle problems like rhabdomyolysis (severe muscle breakdown), and an increase in blood sugar levels, which could lead to diabetes.

Comes with several important warnings. It should not be used during pregnancy or breastfeeding due to the risk of serious harm to the fetus or infant. It can also cause severe muscle problems, including rhabdomyolysis, which can lead to kidney failure. Patients with liver disease or high alcohol consumption should avoid using Lipitor, as it may lead to further liver damage. Additionally, grapefruit and grapefruit juice should be avoided, as they can increase the level of atorvastatin in the bloodstream, raising the risk of side effects. Regular monitoring of liver function and muscle health is advised while on this medication, and people with a history of diabetes should be aware that Lipitor can increase blood sugar levels​.

Overdose, symptoms may include muscle pain, weakness, nausea, vomiting, and diarrhea. More severe effects may involve liver damage and kidney failure due to rhabdomyolysis (muscle breakdown). If you suspect an overdose, it is crucial to seek immediate medical attention. Prompt treatment can help manage any serious complications​.