Trazodone tablets (Desyrel) are primarily used to treat major depressive disorder by improving mood and relieving feelings of sadness or hopelessness. It works by increasing serotonin levels in the brain, which helps regulate mood and emotions. In addition to its primary use for depression, trazodone is frequently prescribed off-label to treat insomnia due to its sedative properties, making it helpful for individuals who struggle with sleep disturbances, especially those related to depression. Trazodone is also used to manage anxiety, particularly when it co-occurs with depression or sleep issues, by helping to balance serotonin levels. Additionally, it has off-label uses for conditions such as chronic pain, post-traumatic stress disorder (PTSD), and some types of headaches. Its versatility in treating mood disorders, sleep problems, and anxiety makes trazodone an important medication in managing both mental health and related conditions.
Common side effects of trazodone include drowsiness, dizziness, dry mouth, blurred vision, and constipation. Some people may experience more serious side effects like low blood pressure, priapism (a painful erection that can last for hours), or serotonin syndrome, a potentially life-threatening condition when serotonin levels become too high.
Trazodone should be used with caution in individuals with a history of heart problems, seizures, or liver issues. It can interact with other medications, particularly other antidepressants or medications that affect serotonin levels. It may also increase the risk of suicidal thoughts or behaviors, especially in younger individuals, and should be monitored closely. Trazodone should not be taken with alcohol or sedatives, as this can increase the risk of severe drowsiness and other side effects. Always consult a healthcare provider before discontinuing or changing the dosage of trazodone.
An overdose of trazodone (Desyrel) can be dangerous and requires immediate medical attention. Symptoms of a trazodone overdose may include severe drowsiness or sedation, dizziness, and a rapid or irregular heartbeat. Low blood pressure (hypotension) is also common, which can lead to fainting or shock. In more severe cases, an overdose may cause seizures, respiratory depression (slow or difficulty breathing), confusion, nausea, or vomiting. If left untreated, a trazodone overdose can lead to serious complications such as coma, cardiac arrest, or serotonin syndrome, a life-threatening condition. Serotonin syndrome can cause symptoms like agitation, fever, muscle rigidity, and confusion. If an overdose is suspected, it’s essential to seek emergency medical care immediately to ensure proper treatment and prevent serious health consequences.